Knowledge, attitudes, and practices toward chemotherapy resistance among oncologists: a multinational cross-sectional study - Summary - MDSpire

Knowledge, attitudes, and practices toward chemotherapy resistance among oncologists: a multinational cross-sectional study

  • By

  • Bassam Abdul Rasool Hassan

  • Ali Haider Mohammed

  • Khalis Mohamed

  • Vladimir Yu. Startsev

  • Chema Drira

  • Omar Hamdy

  • Miada Mohamed Fahmi Elmetwaly

  • Said Nabil

  • Shamma Alshehhi

  • Gamil Othman

  • Hamoud H. Y. Al-Hussaini

  • Ahmed Zuhair Abdulhameed Alsammarraie

  • Arooj Abid

  • Nada M. Kassem

  • Sami El Khatib

  • Souheil Hallit

  • Diana Malaeb

  • Hassan Hosseini

  • June 5, 2026

  • 0 min

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Objective:

To assess oncologists’ knowledge, attitudes, and practices regarding chemotherapy resistance across multiple countries, highlighting gaps in understanding.

Key Findings:
  • 3,779 oncologists participated, with a mean age of 36.92 years; 53.1% were female. The largest proportion of participants was from Iraq (21.4%).
  • Most participants were medical oncologists (50.0%), followed by clinical oncologists (23.4%) and radiation oncologists (18.8%).
  • Oncologists aged ≥56 years had lower odds of good knowledge (OR = 0.76).
  • Female participants had higher odds of good knowledge (OR = 1.22) and positive attitudes (OR = 1.20).
  • Post-doctorate holders had greater odds of good knowledge (OR = 1.57) and positive attitudes (OR = 1.50).
  • Longer professional experience and previous exposure to chemotherapy resistance cases were associated with better knowledge and attitudes.
Interpretation:

The findings highlight important gaps in oncologists’ knowledge and practices regarding chemotherapy resistance.

Limitations:
  • The study may not fully represent all oncologists globally due to the selection of specific countries, including Morocco, Tunisia, Egypt, Yemen, the United Arab Emirates, Russia, Pakistan, Iraq, and China.
  • Responses may be influenced by self-reporting bias.
Conclusion:

Targeted educational programs and continuous professional development, particularly in underrepresented regions, may help strengthen clinical preparedness and improve chemotherapy resistance management.

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