Cardiac magnetic resonance imaging in patients referred for premature ventricular contractions: identifying patients most likely to benefit - Summary - MDSpire

Cardiac magnetic resonance imaging in patients referred for premature ventricular contractions: identifying patients most likely to benefit

  • By

  • Amélie Gomez

  • Mesut Gun

  • Akli Otmani

  • Laurent Leborgne

  • Christophe Tribouilloy

  • Emmanuelle Vermes

  • July 1, 2026

  • 0 min

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Objective:

To assess the ability of CMR to detect structural abnormalities in patients referred for PVCs and to determine predictive factors.

Approach:
  • Study Population: 200 consecutive patients referred for CMR with PVCs were retrospectively included after an initial workup.
  • Data Collection: Clinical and laboratory data were collected from electronic medical records, and PVC morphology was classified.
  • CMR Acquisitions: CMR examinations were performed using 1.5 Tesla and 3 Tesla magnets, assessing LV and RV function and wall motion.
Key Findings:
  • CMR revealed structural abnormalities in 92 patients (46% of cases): nonischemic fibrosis (n = 53, 26.5%), ischemic fibrosis (n = 18, 9%), mixed fibrosis (n = 4, 2%), and 4 (2%) cardiomyopathies.
  • Predictive factors for structural abnormalities included age (odds ratio [OR]: 1.03; p = 0.016), male sex (OR: 2.48; p = 0.019), diabetes (OR: 5.02; p = 0.010), smoking (OR: 2.09; p = 0.047), known cardiomyopathy (OR: 3.24; p = 0.006), pleomorphic PVCs (OR: 2.48; p = 0.051), and the absence of a decrease in PVC frequency during exercise (OR: 0.24; p < 0.001).
  • Young, nondiabetic patients with normal echocardiography and monomorphic PVCs that decreased with effort had normal CMR findings.
Interpretation:

CMR is useful in investigating PVCs, detecting structural abnormalities that may not be identified in initial assessments.

Limitations:
  • The study was retrospective and conducted at a single center.
  • Findings may not be generalizable to all patient populations.
Conclusion:

CMR can detect structural heart disease in PVC patients, with specific predictive factors identified.

Original Source(s)

Cardiac magnetic resonance imaging in patients referred for premature ventricular contractions: identifying patients most likely to benefit

  • by Amélie Gomez, Mesut Gun, Akli Otmani, Laurent Leborgne, Christophe Tribouilloy, Emmanuelle Vermes

  • July 1, 2026

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