Trends in Research on Autoimmune Liver Disorders and Gut Microbiota (1989–2025): A Bibliometric and Visualization Study Utilizing the Web of Science Core Collection Database - Summary - MDSpire
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Trends in Research on Autoimmune Liver Disorders and Gut Microbiota (1989–2025): A Bibliometric and Visualization Study Utilizing the Web of Science Core Collection Database
To conduct a comprehensive bibliometric analysis of research trends and hot topics related to autoimmune liver diseases (AILD) and gut microbiota from 1989 to 2025.
Key Findings:
Research on AILD and gut microbiota has grown significantly, involving 58 countries and 3,528 authors.
Influential journals include Frontiers in Immunology, GUT, and World Journal of Gastroenterology.
Key topics identified include Mendelian randomization, primary sclerosing cholangitis, and the gut-liver axis.
Interpretation:
The study highlights the increasing recognition of gut microbiota's role in AILD, suggesting a shift towards exploring therapeutic targets through microbiome modulation, which could inform future research directions.
Limitations:
Most studies are cross-sectional or small-sample cohort studies.
Current research often focuses on single disease models and lacks comprehensive longitudinal studies, limiting generalizability.
Conclusion:
The bibliometric analysis reveals a rapid growth in research on AILD and gut microbiota, emphasizing the need for further exploration of microbiota modulation in treatment strategies, aligning with trends in existing literature.