Trends in Research on Autoimmune Liver Disorders and Gut Microbiota (1989–2025): A Bibliometric and Visualization Study Utilizing the Web of Science Core Collection Database - Summary - MDSpire

Trends in Research on Autoimmune Liver Disorders and Gut Microbiota (1989–2025): A Bibliometric and Visualization Study Utilizing the Web of Science Core Collection Database

  • By

  • Ying Wan

  • Mengyao Zheng

  • Wen Fu

  • Huiling Zhu

  • Yuting Li

  • Huiying Lin

  • Jie Chen

  • Jianwei Li

  • Qiulan Mo

  • Wenlin Tai

  • Jinhui Yang

  • April 29, 2026

  • 0 min

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Objective:

To conduct a comprehensive bibliometric analysis of research trends and hot topics related to autoimmune liver diseases (AILD) and gut microbiota from 1989 to 2025.

Key Findings:
  • Research on AILD and gut microbiota has grown significantly, involving 58 countries and 3,528 authors.
  • Influential journals include Frontiers in Immunology, GUT, and World Journal of Gastroenterology.
  • Key topics identified include Mendelian randomization, primary sclerosing cholangitis, and the gut-liver axis.
Interpretation:

The study highlights the increasing recognition of gut microbiota's role in AILD, suggesting a shift towards exploring therapeutic targets through microbiome modulation, which could inform future research directions.

Limitations:
  • Most studies are cross-sectional or small-sample cohort studies.
  • Current research often focuses on single disease models and lacks comprehensive longitudinal studies, limiting generalizability.
Conclusion:

The bibliometric analysis reveals a rapid growth in research on AILD and gut microbiota, emphasizing the need for further exploration of microbiota modulation in treatment strategies, aligning with trends in existing literature.

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