Nurse-evaluated intrinsic capacity predicts rehospitalization risk in coronary artery disease patients post-percutaneous coronary intervention - Summary - MDSpire

Nurse-evaluated intrinsic capacity predicts rehospitalization risk in coronary artery disease patients post-percutaneous coronary intervention

  • By

  • Yuning Zhao

  • Wenwen Zhang

  • Jing Yang

  • Yuqi Fang

  • Yizhu Yan

  • Guangyao Zhai

  • April 20, 2026

  • 0 min

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Objective:

To investigate the association between intrinsic capacity (IC) and hospital readmission in patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI), highlighting the novelty of this research.

Key Findings:
  • Higher IC score (indicating poorer IC) was independently associated with increased all-cause rehospitalization risk (HR = 3.07, 95% CI 1.89–5.00).
  • Higher IC score was also linked to increased cardiovascular rehospitalization risk (HR = 5.23, 95% CI 2.30–11.89).
  • IC score was not a significant predictor of non-cardiovascular rehospitalization.
  • RCS curves indicated a linear positive relationship between IC score and HR of cardiac rehospitalization with a cutoff of 2.5.
  • ROC curve for all-cause rehospitalization showed IC score with an AUC of 0.692 (95% CI: 0.664–0.729).
Interpretation:

IC score serves as an accessible, independent, and robust predictor of cardiovascular rehospitalization after PCI in CAD patients, with implications for personalized care.

Limitations:
  • Retrospective design may introduce bias.
  • Single-center study limits generalizability and may affect the applicability of findings.
  • Potential confounding factors not fully controlled.
Conclusion:

Assessing intrinsic capacity can enhance personalized risk stratification and long-term care planning for CAD patients post-PCI, emphasizing its clinical relevance.

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