To evaluate the application of Canadian treat-to-target (T2T) criteria in clinical practice for moderate-to-severe plaque psoriasis, emphasizing the significance of the association between target achievement and treatment continuation.
Key Findings:
73.3% of patients achieved treatment targets, indicating effective management strategies.
98.4% of patients who met targets continued biologic therapy, suggesting a strong link between target achievement and treatment adherence.
Nearly half of patients not meeting targets remained on treatment, influenced by DLQI and shared decision-making, highlighting the need for personalized treatment approaches.
Interpretation:
The findings support the clinical relevance of Canadian T2T criteria and highlight the importance of individualized care, patient quality of life, and physician judgment in treatment decisions, suggesting practical ways to implement these considerations.
Limitations:
The study is based on retrospective chart reviews, which may introduce bias affecting the reliability of the findings.
Limited geographic representation despite efforts to include diverse practices, which may affect the generalizability of the results.
Conclusion:
The study underscores the effectiveness of T2T approaches in psoriasis management and the need for ongoing evaluation of treatment strategies in real-world settings, especially as treatment options evolve.
