Large endometrial polyps in postmenopausal women lacking hormonal influence: a case study and review of existing literature - Summary - MDSpire

Large endometrial polyps in postmenopausal women lacking hormonal influence: a case study and review of existing literature

  • By

  • Danlin Wang

  • Li Wang

  • Ning Zhou

  • Yan Fang

  • April 20, 2026

  • 0 min

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Objective:

To summarize the clinical presentation and management of giant endometrial polyps in postmenopausal women without hormonal exposure, including a review of existing literature.

Key Findings:
  • Patients aged 55 to 70 years with polyp diameters from 4.0 to 12.0 cm.
  • Postmenopausal bleeding was the most common symptom.
  • Surgical interventions included total abdominal hysterectomy with bilateral salpingo-oophorectomy, hysteroscopic polypectomy, and dilation and curettage.
  • Most polyps (11/15) were benign, exhibiting cystic dilatation.
Interpretation:

Giant endometrial polyps in postmenopausal women are rare but predominantly benign, particularly in the absence of hormonal exposure. Transvaginal sonography is effective for initial evaluation, while diagnostic hysteroscopy is the gold standard for management.

Limitations:
  • Small sample size of cases reviewed.
  • Potential publication bias in literature retrieval.
  • Limited generalizability due to the small sample size.
Conclusion:

Giant endometrial polyps can occur in postmenopausal women without hormonal influence and are mostly benign. Accurate diagnosis and management are crucial to avoid unnecessary aggressive surgery.

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