Clinical Case Study: Post-Surgical Antiviral Intervention Following Pterygium Excision Informed by Corneal Confocal Microscopy - Summary - MDSpire

Clinical Case Study: Post-Surgical Antiviral Intervention Following Pterygium Excision Informed by Corneal Confocal Microscopy

  • By

  • Fangfang Jin

  • Wenwei Li

  • Ting Wu

  • Bin Wang

  • April 28, 2026

  • 0 min

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Objective:

To investigate the etiology of corneal complications following pterygium excision using corneal confocal microscopy, emphasizing its clinical significance.

Key Findings:
  • The patient developed herpes simplex keratitis as a complication post-pterygium surgery, indicating a need for vigilance.
  • Corneal confocal microscopy revealed irregularities in the corneal epithelium and inflammatory cell activity, suggesting underlying viral infection.
  • Antiviral treatment led to improvement in the patient's ocular condition, highlighting the effectiveness of timely intervention.
Interpretation:

The findings suggest that herpes simplex keratitis can occur as a rare complication after pterygium surgery, highlighting the need for thorough diagnostic evaluation in such cases.

Limitations:
  • The study is based on a single case, limiting generalizability.
  • Long-term outcomes of the antiviral treatment were not assessed.
  • The lack of diverse patient demographics limits the applicability of findings.
Conclusion:

In cases of suspected viral infection following pterygium surgery, early diagnosis and targeted treatment are crucial for a favorable visual prognosis, with corneal confocal microscopy playing a key role.

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