Association Between Systemic Immune-Inflammation Index and Postoperative Optical Quality in the Early Recovery Phase After Cataract Surgery: A Retrospective Study - Summary - MDSpire
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Association Between Systemic Immune-Inflammation Index and Postoperative Optical Quality in the Early Recovery Phase After Cataract Surgery: A Retrospective Study
To investigate the association between preoperative systemic immune-inflammation index (SII) and early objective optical quality following phacoemulsification cataract surgery.
Approach:
Key Findings:
Higher preoperative log2-SII was significantly associated with lower internal MTF average height at postoperative 1 week and 1 month.
No significant association was found at 1 day postoperative.
Exploratory analyses indicated that the low-SII group had better internal Strehl ratio, lower total higher-order aberrations, and higher dysfunctional lens index at 1 month.
Interpretation:
Higher preoperative SII was associated with less favorable early postoperative internal MTF average height, suggesting systemic inflammatory status may influence early optical recovery.
Limitations:
Findings from exploratory analyses require confirmation in future studies.
Postoperative visual acuity did not differ between groups, indicating that SII may affect optical quality without impacting visual acuity.
Conclusion:
Despite comparable visual acuity, systemic inflammatory status may contribute to interindividual variability in early optical recovery after cataract surgery.
As cataract surgery continues to evolve, the focus is shifting beyond the operating theatre to the weakest part of the patient pathway – postoperative drops
