Papillary thyroid carcinoma with brain and lung metastases: a case report - Summary - MDSpire

Papillary thyroid carcinoma with brain and lung metastases: a case report

  • By

  • Ying Zhao

  • Xiaohua Chen

  • Xin Bai

  • Shujun Guo

  • Min Gao

  • Xiaohan Liu

  • Jianming Tang

  • May 25, 2026

  • 0 min

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Objective:

To report a rare case of papillary thyroid carcinoma (PTC) with delayed multiple metastases to the brain and lungs, highlighting the clinical significance of such occurrences.

Key Findings:
  • The patient developed brain and lung metastases six years after total thyroidectomy for PTC, underscoring the potential for late recurrence.
  • Anlotinib treatment resulted in partial remission of lung metastases, suggesting its viability as a treatment option in resistant cases.
Interpretation:

This case highlights the potential for delayed and uncommon distant metastases in PTC, emphasizing the need for ongoing surveillance and consideration of alternative treatments.

Limitations:
  • The case is a single report and may not represent broader trends in PTC metastasis, limiting its applicability.
  • Limited follow-up duration may not capture long-term outcomes, necessitating further studies.
Conclusion:

The findings suggest that PTC can lead to delayed metastases, and anlotinib may be a viable treatment option, reinforcing the importance of lifelong monitoring for patients.

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