Assessment of Corneal Stability and Visual Outcomes in Myopic Patients in China Two Years After FS-LASIK with Preventive Corneal Crosslinking - Summary - MDSpire

Assessment of Corneal Stability and Visual Outcomes in Myopic Patients in China Two Years After FS-LASIK with Preventive Corneal Crosslinking

  • By

  • Jiayu Li

  • Yuyan Huang

  • Yushan Xu

  • Zecheng Wang

  • Yanzheng Song

  • Fengju Zhang

  • March 5, 2026

  • 0 min

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Objective:

To explore long-term visual quality, corneal morphology, and biomechanics in myopic patients undergoing FS-LASIK with and without prophylactic corneal crosslinking (CXL), highlighting the significance of these findings in the context of existing literature.

Key Findings:
  • FS-LASIK Xtra showed favorable visual outcomes and corneal stability compared to FS-LASIK alone, with a statistically significant improvement in visual acuity.
  • Corneal biomechanics improved significantly in the FS-LASIK Xtra group, as measured by specific biomechanical indices.
  • No significant increase in corneal ectasia was observed in patients undergoing FS-LASIK Xtra, supporting its safety profile.
Interpretation:

The addition of prophylactic CXL to FS-LASIK appears to enhance corneal stability and visual outcomes in myopic patients, particularly those at risk of ectasia.

Limitations:
  • Retrospective design may introduce selection bias.
  • Long-term follow-up beyond two years is needed to assess the durability of outcomes.
  • Sample size may limit the generalizability of findings, and demographic diversity should be considered.
Conclusion:

FS-LASIK with prophylactic CXL is a promising approach for myopic correction in at-risk patients, offering improved corneal stability and visual quality, with important implications for clinical practice.

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