Pharmacist Outreach and SGLT2 Inhibitor Uptake in Patients With Diabetes and Chronic Kidney Disease - Summary - MDSpire

Pharmacist Outreach and SGLT2 Inhibitor Uptake in Patients With Diabetes and Chronic Kidney Disease

  • By

  • Deborah L. Pestka

  • Daniel Murphy

  • Adam N. Kaplan

  • Brent C. Taylor

  • Pearl Huynh

  • Jessica A. Rechtzigel

  • Shari Kjos

  • Lisa Marie Ellich

  • Melissa Atwood

  • Beth A. Polsfuss

  • Amber R. Thomas

  • Joseph Y. Lee

  • Areef Ishani

  • May 18, 2026

  • 0 min

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Objective:

To assess whether pharmacists’ proactive outreach to patients with CKD and type 2 diabetes would be associated with increased initiation of SGLT2 inhibitor use, specifically measuring initiation rates and patient outcomes.

Key Findings:
  • SGLT2 inhibitors significantly reduce CKD progression and improve patient outcomes, with initiation rates increasing by X% in the intervention group.
  • Pharmacists can effectively identify and initiate treatment with SGLT2 inhibitors in eligible patients.
  • Low prescribing patterns of SGLT2 inhibitors indicate a need for proactive outreach.
Interpretation:

The study suggests that pharmacist-led interventions can enhance the initiation of SGLT2 inhibitors among patients with CKD and diabetes, addressing underutilization of these beneficial medications.

Limitations:
  • The pseudorandomization method may not ensure perfect balance in patient characteristics, potentially affecting the study's validity.
  • The study did not require informed consent, which may limit generalizability.
Conclusion:

Engaging pharmacists in the management of CKD and diabetes can improve the initiation of SGLT2 inhibitors, potentially leading to better patient outcomes and addressing current underutilization.

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