A comparative study of mirabegron versus doxazosin in improving ureteral stent-related dysfunction - Summary - MDSpire

A comparative study of mirabegron versus doxazosin in improving ureteral stent-related dysfunction

  • By

  • Bo Tao

  • Enyan Jiang

  • Yuan Zhao

  • Zhangxiao Xu

  • Juan Yang

  • Lijun Wang

  • May 13, 2025

  • 0 min

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Objective:

To compare the efficacy and side effects of mirabegron and doxazosin in alleviating ureteral stent symptoms, with a specific focus on sexual dysfunction as a symptom.

Key Findings:
  • Both mirabegron and doxazosin were effective in reducing ureteral stent-related symptoms.
  • Mirabegron showed a potential advantage in alleviating sexual dysfunction compared to doxazosin.
  • Adverse effects were monitored, with both medications demonstrating a favorable safety profile.
Interpretation:

The study suggests that mirabegron may be a viable alternative to doxazosin for managing ureteral stent-related symptoms, particularly regarding sexual dysfunction.

Limitations:
  • Single-center study may limit generalizability.
  • Short follow-up duration post-stent removal may affect the reliability of long-term outcomes.
Conclusion:

Mirabegron appears to be an effective option for managing ureteral stent-related symptoms, particularly benefits for sexual dysfunction, warranting further investigation to validate these findings.

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