Machine learning clustering of psychological response trajectories across the first and second waves of the COVID-19 pandemic - Summary - MDSpire

Machine learning clustering of psychological response trajectories across the first and second waves of the COVID-19 pandemic

  • By

  • Fardous Hasan

  • Farzana Haque

  • Roberto Ariel Abeldaño Zuñiga

  • Nourhan M. Aly

  • Moréniké Oluwátóyìn Foláyan

  • June 26, 2026

  • 0 min

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Objective:

To assess how person-centered psychological clusters emerge and evolve across the initial two waves of the COVID-19 pandemic.

Approach:
  • Study Design: Longitudinal study assessing 338 adults across two pandemic waves (2020 and 2021) using validated instruments for PTSS, coping strategies, and pandemic stress.
  • Clustering Methodology: Machine learning clustering (K-means and Gaussian mixture models) evaluated solutions k = 2–6 using various statistical criteria.
Key Findings:
  • Three statistically defined clusters emerged at both waves: a low-distress, high-coping cluster (labeled 'resilient'; Wave 1: 35.5%; Wave 2: 29.00%); a low-coping cluster (40.04%; 49.11%); and a high-distress cluster (25.06%; 21.89%).
  • Overall, 55.3% (95% CI [50.0%, 60.5%]) remained in the same cluster across waves.
  • Among those initially in the resilient cluster, 55.8% transitioned to higher-distress clusters by Wave 2.
  • The low-coping cluster showed the greatest stability (68.9%), and 50.6% of those initially in the high-distress cluster transitioned to lower-distress clusters.
Interpretation:

Psychological responses to prolonged crises are dynamic and heterogeneous, influenced by coping capacity and socioeconomic factors.

Limitations:
  • Observational design limits causal inferences.
  • Convenience sampling may affect generalizability.
Conclusion:

These findings suggest that further research with more frequent assessments and experimental designs is needed.

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