Remimazolam Is Associated with Superior Cerebral and Pulmonary Protection over Propofol in Elderly Thoracic Surgery: A Real-World Study Validated by Propensity Score Matching - Summary - MDSpire

Remimazolam Is Associated with Superior Cerebral and Pulmonary Protection over Propofol in Elderly Thoracic Surgery: A Real-World Study Validated by Propensity Score Matching

  • By

  • Zhang, Jingjing

  • Zhang, Xiaoyan

  • Cao, Na

  • Cai, Yichao

  • Zhao, Caixia

  • Tang, Chunying

  • Ma, Zhenhua

  • Zhang, Yan

  • May 6, 2026

  • 0 min

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Objective:

To compare the real-world outcomes of remimazolam and propofol in elderly patients undergoing elective VATS lobectomy.

Key Findings:
  • Remimazolam group showed superior cognitive recovery with higher MMSE scores at multiple time points post-surgery.
  • Better pulmonary function in the remimazolam group at 72 hours, with higher FEV₁% predicted and lower lung ultrasound scores.
  • Enhanced hemodynamic and cerebral oxygen stability in the remimazolam group.
  • Lower incidence of postoperative delirium and pulmonary complications in the remimazolam group.
Interpretation:

Limitations:
Conclusion:

Original Source(s)

Remimazolam Is Associated with Superior Cerebral and Pulmonary Protection over Propofol in Elderly Thoracic Surgery: A Real-World Study Validated by Propensity Score Matching

  • by Zhang, Jingjing , Zhang, Xiaoyan , Cao, Na , Cai, Yichao , Zhao, Caixia , Tang, Chunying , Ma, Zhenhua , Zhang, Yan

  • May 6, 2026

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