Prognostic Implications of Post-Endovascular Therapy Contrast Staining in Basilar Artery Occlusion Stroke - Summary - MDSpire

Prognostic Implications of Post-Endovascular Therapy Contrast Staining in Basilar Artery Occlusion Stroke

  • By

  • Natascha Hohmann

  • Matthias P. Fabritius

  • Sijing Gu

  • Daniel Puhr-Westerheide

  • Philipp Lohse

  • Steffen Tiedt

  • Lars Kellert

  • Konstantinos Dimitriadis

  • Sergio Grosu

  • Thomas Liebig

  • Jens Ricke

  • Wolfgang G. Kunz

  • Osman Öcal

  • Paul Reidler

  • April 28, 2026

  • 0 min

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Objective:

To determine the prognostic significance of post-interventional contrast staining in patients with basilar artery occlusion stroke following endovascular therapy, specifically its impact on clinical outcomes.

Key Findings:
  • 42 patients included, with 18 (42.9%) showing contrast staining on CT.
  • Patients with contrast staining had significantly worse outcomes (median mRS: 6 vs. 2, p < 0.001).
  • Contrast staining was a strong predictor of unfavorable functional outcomes, surpassing other imaging parameters, with a significant volume correlation.
Interpretation:

Post-interventional contrast staining is a significant indicator of poor functional recovery in BAO stroke patients after EVT, highlighting its potential role in predicting clinical outcomes and guiding treatment decisions.

Limitations:
  • Retrospective design may introduce selection bias, potentially affecting the generalizability of the findings.
  • Limited generalizability due to the specific patient population and setting.
Conclusion:

Contrast staining on postinterventional CT is a robust predictor of unfavorable outcomes in BAO stroke patients treated with EVT.

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