Trends in Incidence and Epidemiology of Methicillin-Resistant Staphylococcus aureus Bacteremia, Six Emerging Infections Program Surveillance Sites, 2005–2022 - Summary - MDSpire
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Trends in Incidence and Epidemiology of Methicillin-Resistant Staphylococcus aureus Bacteremia, Six Emerging Infections Program Surveillance Sites, 2005–2022
To assess the trends in MRSA bacteremia incidence and epidemiology during the COVID-19 pandemic compared to prepandemic trends, focusing on specific changes in hospital-onset and community-associated infections.
Key Findings:
Overall MRSA bacteremia incidence declined from 2005 to 2016 but reversed from 2016 to 2019.
Hospital-onset incidence increased during 2020-2022 compared to 2016-2019.
Community-associated incidence was lower than predicted during 2020-2022.
The proportion of MRSA cases with recent COVID-19 was highest among hospital-onset infections.
Interpretation:
The COVID-19 pandemic significantly impacted MRSA bacteremia trends, particularly increasing hospital-onset infections, while community-associated infections saw a reversal of prepandemic increases, likely due to changes in healthcare access and infection control measures.
Limitations:
The study is limited to six surveillance sites, which may not represent national trends, potentially affecting the generalizability of the findings.
Potential confounding factors related to COVID-19 mitigation measures were not fully explored, which could influence the observed trends.
Conclusion:
The findings highlight the need for enhanced infection prevention strategies, especially in populations with recent COVID-19, and suggest that pandemic-related measures may have influenced MRSA epidemiology, necessitating further investigation.
by Holly M Biggs, Rongxia Li, Kelly A Jackson, Joelle Nadle, Susan Petit, Susan M Ray, Ruth Lynfield, Kathryn Como-Sabetti, Ghinwa Dumyati, Anita Gellert, Marissa Walsh, William Schaffner, James Baggs, Isaac See
A global systematic review of 173 studies found differing associations between COVID-19 infection and vaccination and retinal vascular events, with retinal artery occlusion more common after infection and retinal vein occlusion more common after vaccination.
