Neurobehavioral outcomes and associated risk factors in pediatric brain tumor survivors - Summary - MDSpire

Neurobehavioral outcomes and associated risk factors in pediatric brain tumor survivors

  • By

  • Yuliang Wang

  • Wing Lam Chan

  • Fei Li

  • Jiaoyang Cai

  • Yin Ting Cheung

  • Eric Tsz Him Lai

  • Oscar Lok Kan Leung

  • Shiting Liang

  • Dennis Tak Loi Ku

  • Matthew Ming Kong Shing

  • Eric Chun Ho Fu

  • Jeffrey Ping Wa Yau

  • Anselm Chi Wai Lee

  • Evelyn Ruoyun Lu

  • Alex Wing Kwan Leung

  • Frankie Wai Tsoi Cheng

  • Wilson Wai Shing Ho

  • Zeng Gao

  • Ye Song

  • Stephenie Ka Yee Liu

  • Lucia Tsang

  • Ada Nga Yee Yuen

  • Tatia Mei Chun Lee

  • Godfrey Chi Fung Chan

  • Anthony Pak Yin Liu

  • Winnie Wan Yee Tso

  • April 11, 2026

  • 0 min

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Objective:

To investigate the prevalence and symptom burden of ADHD, ASD, and emotional and behavioral difficulties among pediatric brain tumor survivors (PBTS), specifically focusing on the types and severity of these impairments, and explore risk factors for neurobehavioral impairments.

Key Findings:
  • PBTS are at risk of neurobehavioral impairments, including ADHD and ASD symptoms, with genetic factors potentially increasing susceptibility.
  • Treatment-related factors such as cranial radiation therapy contribute to neurocognitive and neurobehavioral deficits.
Interpretation:

The study highlights the significant neurobehavioral challenges faced by PBTS, emphasizing the need for comprehensive monitoring and support post-treatment to enhance their quality of life.

Limitations:
  • The study relies on retrospective data, which may be subject to biases.
  • Limited generalizability due to the specific population studied in Hong Kong.
  • Potential confounding variables may not have been adequately controlled.
Conclusion:

PBTS require ongoing assessment and intervention for neurobehavioral issues to improve their quality of life and psychosocial outcomes.

Original Source(s)

Neurobehavioral outcomes and associated risk factors in pediatric brain tumor survivors

  • by Yuliang Wang, Wing Lam Chan, Fei Li, Jiaoyang Cai, Yin Ting Cheung, Eric Tsz Him Lai, Oscar Lok Kan Leung, Shiting Liang, Dennis Tak Loi Ku, Matthew Ming Kong Shing, Eric Chun Ho Fu, Jeffrey Ping Wa Yau, Anselm Chi Wai Lee, Evelyn Ruoyun Lu, Alex Wing Kwan Leung, Frankie Wai Tsoi Cheng, Wilson Wai Shing Ho, Zeng Gao, Ye Song, Stephenie Ka Yee Liu, Lucia Tsang, Ada Nga Yee Yuen, Tatia Mei Chun Lee, Godfrey Chi Fung Chan, Anthony Pak Yin Liu, Winnie Wan Yee Tso

  • April 11, 2026

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