To summarize the clinical characteristics, disease progression, risk factors, ECG, imaging features, and early intervention strategies for patients with de Winter syndrome.
Key Findings:
Median age of patients was 53.7 years, predominantly male (93.3%).
Primary risk factors included smoking (48.5%) and hypertension (30.5%).
Chest pain was the main presenting symptom (98.0%).
The de Winter pattern was most frequently observed in leads V4 (91.4%) and V3 (90.5%).
Dynamic ECG changes were noted, with 22.9% of patients progressing to STEMI.
Coronary angiography revealed lesions mainly in the left anterior descending artery (84.6%).
Major complications occurred in 32.6% of patients during hospitalization.
Interpretation:
The presence of the de Winter pattern on ECG suggests significant coronary occlusion, particularly in the left anterior descending artery.
Limitations:
The study is retrospective and may have selection bias.
Data was collected from a single center and may not be generalizable.
Conclusion:
Improving recognition of de Winter syndrome is crucial for enhancing patient outcomes.