Vaccinome Landscape in Nearly 620 000 Patients With Diabetes - Summary - MDSpire

Vaccinome Landscape in Nearly 620 000 Patients With Diabetes

  • By

  • Francesca D’Addio

  • Elisa Lazzaroni

  • Maria Elena Lunati

  • Giuseppe Preziosi

  • Michele Ercolanoni

  • Giulio Turola

  • Chiara Marrocu

  • Giovanni Cicconi

  • Sudwaric Sharma

  • Simona Scarioni

  • Laura Montefusco

  • Ida Pastore

  • Paola Silvia Morpurgo

  • Antonio Rossi

  • Alessandra Gandolfi

  • Camilla Tinari

  • Giada Rossi

  • Moufida Ben Nasr

  • Cristian Loretelli

  • Roberta Maria Fiorina

  • Baldassarre Grassa

  • Rosa Terranova

  • Loredana Bucciarelli

  • Cesare Berra

  • Danilo Cereda

  • Gianvincenzo Zuccotti

  • Catia Rosanna Borriello

  • Paolo Fiorina

  • July 23, 2024

  • 0 min

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Objective:

To analyze the immunization coverage and its impact on mortality and hospitalization among patients with type 1 and type 2 diabetes in Lombardy, Italy, highlighting its significance for public health.

Key Findings:
  • 44.6% of patients with diabetes received the influenza vaccine.
  • 10.9% received the pneumococcal vaccine, 2.5% the antimeningococcus vaccine, and 0.7% the antizoster vaccine.
  • Vaccinated patients showed a 2-fold reduction in overall mortality risk and decreased hospitalizations, particularly for cardiac and pulmonary causes.
  • Older patients with diabetes had a 3-fold lower risk of mortality after vaccination.
Interpretation:

The study highlights the significant protective effects of vaccination against influenza, zoster, and meningococcus in reducing mortality and hospitalizations among patients with diabetes, emphasizing the need for improved immunization coverage and its implications for healthcare policy.

Limitations:
  • Data on vaccination history prior to the 2021-2022 campaign were not included.
  • The study is based on registry data, which may not capture all relevant health outcomes and could introduce biases.
Conclusion:

Immunization coverage in patients with diabetes remains below recommended targets, but existing vaccinations significantly reduce mortality and hospitalization risks, underscoring the urgent need for enhanced vaccination efforts in this high-risk population.

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