Objective:

To introduce a dynamic navigation paradigm in cardiac rehabilitation using blood metabolomics for personalized risk assessment and intervention.

Approach:

• Dynamic Navigation Paradigm: This review systematically summarizes the application of blood metabolomics in constructing individualized metabolic fingerprints, achieving precise risk stratification, dynamically evaluating rehabilitation responses, and optimizing intervention strategies in real time.

Key Findings:

• Blood metabolomics provides real-time insights into patients' biochemical status, enabling tailored interventions.
• Metabolomic profiles correlate with improvements in cardiac function and exercise capacity.
• Integration of metabolomics allows for the identification of novel biomarkers for risk stratification.

Interpretation:

The integration of blood metabolomics into cardiac rehabilitation offers a transformative opportunity for precision medicine, enhancing individualized patient care.

Limitations:

• The complexity of metabolic pathways and the need for sophisticated analytical techniques can pose significant hurdles.
• Variability in individual metabolic responses complicates clinical application.

Conclusion:

The shift towards personalized cardiac rehabilitation using dynamic metabolic insights has the potential to redefine care standards for cardiovascular patients.