Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation - Summary - MDSpire
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Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation
To assess the association between the Risk Assessment and Management Programme for Hypertension (RAMP-HT) and complications and all-cause mortality compared to usual care over a decade (2012-2018).
Key Findings:
RAMP-HT showed a lower incidence rate of cardiovascular diseases (CVD) compared to usual care (IR 16.54 [95% CI 16.31, 16.78] vs 18.40 [95% CI 18.10, 18.69] cases/1000 person-years).
All-cause mortality was also lower in the RAMP-HT group (IR 9.41 [95% CI 9.24, 9.59] vs 12.23 [95% CI 12.00, 12.47] cases/1000 person-years).
Participants in RAMP-HT had a 9% reduced risk of CVD (HR: 0.91 [95% CI: 0.89, 0.93]) and a 12% reduced risk of all-cause mortality (HR: 0.88 [95% CI: 0.86, 0.90]) compared to usual care.
Interpretation:
The RAMP-HT program, integrating risk assessment and multidisciplinary care, significantly reduces the risk of CVD and all-cause mortality in hypertension patients over a decade, highlighting its potential for broader public health impact.
Limitations:
The study may be subject to biases inherent in observational data despite the use of propensity score matching.
The generalizability of findings may be limited to the specific healthcare setting in Hong Kong.
Potential confounding factors not controlled for may influence the results.
Conclusion:
Integrating RAMP-HT with usual primary care effectively mitigates risks associated with hypertension, supporting its implementation in public health strategies to enhance patient outcomes.
by Zoey Cho Ting Wong, Ivy Lynn Mak, Esther Yee Tak Yu, Emily Tsui Yee Tse, Julie Yun Chen, Weng Yee Chin, David Vai Kiong Chao, Wendy Wing Sze Tsui, Tony King Hang Ha, Eric Yuk Fai Wan, Cindy Lo Kuen Lam