Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation - Summary - MDSpire

Evaluation of hypertension-related complications 10 years after implementation of risk assessment and management programme for hypertension: a target trial emulation

  • By

  • Zoey Cho Ting Wong

  • Ivy Lynn Mak

  • Esther Yee Tak Yu

  • Emily Tsui Yee Tse

  • Julie Yun Chen

  • Weng Yee Chin

  • David Vai Kiong Chao

  • Wendy Wing Sze Tsui

  • Tony King Hang Ha

  • Eric Yuk Fai Wan

  • Cindy Lo Kuen Lam

  • August 4, 2025

  • 0 min

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Objective:

To assess the association between the Risk Assessment and Management Programme for Hypertension (RAMP-HT) and complications and all-cause mortality compared to usual care over a decade (2012-2018).

Key Findings:
  • RAMP-HT showed a lower incidence rate of cardiovascular diseases (CVD) compared to usual care (IR 16.54 [95% CI 16.31, 16.78] vs 18.40 [95% CI 18.10, 18.69] cases/1000 person-years).
  • All-cause mortality was also lower in the RAMP-HT group (IR 9.41 [95% CI 9.24, 9.59] vs 12.23 [95% CI 12.00, 12.47] cases/1000 person-years).
  • Participants in RAMP-HT had a 9% reduced risk of CVD (HR: 0.91 [95% CI: 0.89, 0.93]) and a 12% reduced risk of all-cause mortality (HR: 0.88 [95% CI: 0.86, 0.90]) compared to usual care.
Interpretation:

The RAMP-HT program, integrating risk assessment and multidisciplinary care, significantly reduces the risk of CVD and all-cause mortality in hypertension patients over a decade, highlighting its potential for broader public health impact.

Limitations:
  • The study may be subject to biases inherent in observational data despite the use of propensity score matching.
  • The generalizability of findings may be limited to the specific healthcare setting in Hong Kong.
  • Potential confounding factors not controlled for may influence the results.
Conclusion:

Integrating RAMP-HT with usual primary care effectively mitigates risks associated with hypertension, supporting its implementation in public health strategies to enhance patient outcomes.

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