Association between systemic inflammation response index and risk of major adverse cardiovascular events in adults with and without metabolic syndrome: a prospective cohort study in Shanghai, Pudong - Summary - MDSpire

Association between systemic inflammation response index and risk of major adverse cardiovascular events in adults with and without metabolic syndrome: a prospective cohort study in Shanghai, Pudong

  • By

  • Qiqi Meng

  • Juzhong Ke

  • Xiaonan Wang

  • Hua Qiu

  • Qingping Liu

  • Jiaojiao Gao

  • Jiahui Song

  • Yang Liu

  • Qian Xu

  • Mengyao Wu

  • Bo Huang

  • Yuling Qian

  • Lin Song

  • Xiaonan Ruan

  • Kang Wu

  • Yi Zhou

  • June 16, 2026

  • 0 min

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Objective:

To investigate the prognostic value of the systemic inflammation response index (SIRI) for major adverse cardiovascular events (MACE) among adults with metabolic syndrome (MS), and to determine whether MS status modifies the association between SIRI and incident MACE.

Approach:
    Key Findings:
    • Include specific hazard ratios and confidence intervals for clarity.
    Interpretation:

    Remove unsupported claims.

    Limitations:
    • The study is observational, which limits causal inferences.
    • Potential confounding factors may not have been fully accounted for.
    Conclusion:

    Remove unsupported claims.

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