Epidemiological and Genomic Insights into SARS-CoV-2 in Lebanon: A Prospective Multicenter Analysis from 2020 to 2024 - Summary - MDSpire

Epidemiological and Genomic Insights into SARS-CoV-2 in Lebanon: A Prospective Multicenter Analysis from 2020 to 2024

  • By

  • Fatima Dakroub

  • Celina F. Boutros

  • Diego Teixeira

  • Habib Alkalamouni

  • Nagham Hamzah

  • Nancy Hourani

  • Amani Haddara

  • Samar Dalle

  • Dima Khreis

  • Elsy Tawil

  • Silma Baasiri

  • Zeinab El Zein

  • Mayse Naser

  • Rawan Korman

  • Maher Sraj

  • Yara Salameh

  • Sarah Merhi

  • Kawthar Faour

  • Nadim Tfaily

  • Stephanie Damaj

  • Mohammad Taleb

  • Soha Ghanem

  • Ghenwa Dakdouki

  • Rouba Shaker

  • Imad Chokr

  • David Breish

  • Maria Karam

  • Nada M. Melhem

  • Antoine Abou Fayad

  • Hassan Zaraket

  • Ewan M. Harrison

  • Ghassan M. Matar

  • Ghassan S. Dbaibo

  • January 28, 2026

  • 0 min

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Objective:

To compare clinical characteristics of COVID-19 across four years in Lebanon and identify risk factors associated with mortality, emphasizing the significance of these factors for public health.

Key Findings:
  • The pathogenicity of SARS-CoV-2 has evolved, impacting clinical outcomes, necessitating updated treatment protocols.
  • Variants such as Alpha, Delta, and Omicron have shown differing severity and hospitalization rates, highlighting the need for variant-specific strategies.
  • Immunity from infections and vaccinations has shifted COVID-19 from a pandemic to an endemic phase, indicating a need for ongoing surveillance.
Interpretation:

The study highlights the importance of genomic surveillance and understanding local epidemiological patterns to inform urgent public health strategies in Lebanon.

Limitations:
  • Limited data on the genomic epidemiology of SARS-CoV-2 in Lebanon prior to this study may affect the comprehensiveness of findings.
  • Potential biases in data collection due to reliance on patient self-reporting could impact the reliability of the results.
Conclusion:

Understanding the evolving dynamics of COVID-19 in Lebanon is crucial for effective management and vaccination strategies, underscoring the need for continued research.

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