Influence of Sarcopenia on Ventricular Remodeling Post-Coronary Artery Bypass Grafting in Aged Individuals with Coronary Heart Disease - Summary - MDSpire

Influence of Sarcopenia on Ventricular Remodeling Post-Coronary Artery Bypass Grafting in Aged Individuals with Coronary Heart Disease

  • By

  • Hongfang Li

  • Fangfang Ma

  • Yite Li

  • Zhenyu Su

  • Xugang Wang

  • April 29, 2026

  • 0 min

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Objective:

To investigate the association between sarcopenia and ventricular remodelling after coronary artery bypass grafting (CABG) in elderly patients with coronary heart disease (CHD).

Key Findings:
  • Sarcopenia was identified as an independent risk factor for ventricular remodelling (OR = 2.230, 95% CI 1.37–3.62).
  • Sarcopenia showed a sensitivity of 90.0% and specificity of 47.0% in predicting ventricular remodelling.
Interpretation:

Sarcopenia significantly contributes to the risk of ventricular remodelling post-CABG in elderly patients, indicating the need for targeted interventions to improve outcomes.

Limitations:
  • The study is limited to a specific population (elderly Chinese patients), which may affect generalizability.
  • Potential confounding factors not accounted for in the analysis.
Conclusion:

Sarcopenia is a significant risk factor for ventricular remodelling after CABG in elderly patients with CHD, highlighting the importance of assessing muscle health in this population.

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