Bariatric Surgery Reduces Lens Density - Summary - MDSpire

Bariatric Surgery Reduces Lens Density

  • July 1, 2026

  • 3 min

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Objective:

To evaluate the effects of laparoscopic sleeve gastrectomy (LSG) on corneal and lens optical density in obese patients.

Approach:
  • Study Design: A prospective study evaluating 58 eyes from 58 obese patients undergoing LSG, measuring changes in corneal and lens optical density before and six months after surgery.
  • Measurement Technique: Pentacam HR Scheimpflug imaging was used to assess corneal densitometry (CD) and lens densitometry (LD).
Key Findings:
  • Mean body mass index decreased from 43.4 kg/m² to 31.5 kg/m² after surgery.
  • Corneal densitometry decreased from 15.2 to 12.9 GSU.
  • Lens densitometry fell from 10.9 to 9.8 GSU.
  • Significant reductions in intraocular pressure and central corneal thickness were observed.
  • Changes in corneal and lens densitometry showed a moderate positive correlation.
Interpretation:

Limitations:
  • Single-center design.
  • Modest sample size.
  • Short six-month follow-up period.
  • Lack of evaluation of molecular markers of oxidative stress.
Conclusion:

Sources:

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