Rapid Onset of Action and Quality-of-Life Improvements in Chinese Patients with Plaque Psoriasis Treated with Calcipotriol plus Betamethasone Dipropionate Aerosol Foam in a Randomized Phase 3 Trial - Summary - MDSpire

Rapid Onset of Action and Quality-of-Life Improvements in Chinese Patients with Plaque Psoriasis Treated with Calcipotriol plus Betamethasone Dipropionate Aerosol Foam in a Randomized Phase 3 Trial

  • By

  • Lin Cai

  • Furen Zhang

  • Guoqiang Zhang

  • Yangfeng Ding

  • Yan Zhou

  • Shanshan Li

  • Juan Tao

  • Wei Yan

  • Rong Xiao

  • Bin Yang

  • Jianjun Qiao

  • Xiaoyong Man

  • Zaixing Wang

  • Adam El Mongy Jørgensen

  • Merle Kurvits

  • Jens Strodl Andersen

  • Jianzhong Zhang

  • May 3, 2026

  • 0 min

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Objective:

To evaluate the efficacy and safety of Calcipotriol and Betamethasone Dipropionate aerosol foam compared to ointment in Chinese patients with plaque psoriasis.

Key Findings:
  • Cal/BD foam demonstrated superior efficacy compared to Cal/BD ointment in reducing psoriasis severity.
  • Patients experienced rapid improvements in symptoms and quality of life.
  • The safety profile of Cal/BD foam was comparable to that of Cal/BD ointment.
Interpretation:

The findings suggest that Cal/BD foam is an effective and safe treatment option for plaque psoriasis in Chinese patients, potentially enhancing treatment adherence due to rapid symptom relief.

Limitations:
  • The study was limited to a 4-week treatment duration.
  • Results may not be generalizable to populations outside of China.
Conclusion:

Cal/BD aerosol foam is a promising topical therapy for plaque psoriasis, offering rapid therapeutic effects and improved quality of life for patients.

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