UC Irvine study examines brain health in the oldest-old - Summary - MDSpire

UC Irvine study examines brain health in the oldest-old

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  • May 13, 2026

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Objective:

To investigate the relationship between vascular risk factors and brain health in adults aged 90 and older.

Approach:
    Key Findings:
    • Hypertension and diabetes were not associated with increased brain blood vessel damage in adults aged 90 and older.
    • Certain cardiovascular medications were associated with lower rates of cerebral vascular pathology.
    Interpretation:

    The findings challenge traditional assumptions about vascular risk factors and brain health in the oldest-old population.

    Conclusion:

    The study highlights the complexity of brain aging and supports more individualized approaches to care in the oldest.

    Sources:

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