To report a rare case of Guillain-Barré syndrome (GBS) with reproductive system involvement, emphasizing the unusual nature of this presentation identified through 18F-FDG PET/CT imaging.
Key Findings:
18F-FDG PET/CT demonstrated multifocal hypermetabolism in the central nervous system and reproductive system, highlighting the atypical nature of this case.
Significant involvement of the right testis and right prostate was identified, which is rare in GBS cases.
Histopathological findings confirmed orchitis with a mixed T-cell and B-cell infiltrate, underscoring the inflammatory nature of the reproductive involvement.
Interpretation:
This case expands the phenotypic spectrum of GBS to include extraneural involvement, highlighting the utility of 18F-FDG PET/CT in complex presentations and its implications for clinical practice.
Limitations:
The case is a single report and may not represent broader trends in GBS presentations, limiting generalizability.
Lack of large-scale clinical studies on GBS with reproductive system involvement, which hinders understanding of this rare manifestation.
Conclusion:
The findings suggest that GBS can involve the reproductive system, and 18F-FDG PET/CT is a valuable tool for assessing systemic disease in atypical cases, emphasizing the need for awareness of such presentations.
