Neurophysiological Recovery Following Nerve Transfer Surgery to Restore Upper Limb Function after Cervical Spinal Cord Injury - Summary - MDSpire
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Neurophysiological Rehabilitation After Nerve Transfer Surgery for Enhancing Upper Limb Function in Cervical Spinal Cord Injury Patients

  • By

  • Kyle J. Missen

  • Justin M. Brown

  • Ross M. Mandeville

  • Harvey Wu

  • Sean Bristol

  • Peter K. Broadhurst

  • Erin Brown

  • Christopher Doherty

  • Amy K. Hanlan

  • Russell O'Connor

  • Lawrence R. Robinson

  • Kayton Rotenberg

  • J. Michael Hendry

  • Jana Dengler

  • Michael J. Berger

  • July 6, 2026

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Objective:

To evaluate neurophysiological recovery after nerve transfer surgery in SCI using data from needle electromyography (EMG) examinations.

Approach:
  • Method: label
  • Method: text
Key Findings:
  • Nerve transfer surgery improves upper limb muscle strength and functional scores in SCI patients.
  • There is significant variability in treatment response between individuals and different nerve transfers.
  • Longer axonal regeneration distances are associated with slower reinnervation timelines.
Interpretation:

Understanding neurophysiological recovery profiles is crucial for setting patient expectations and providing prognostic information during recovery.

Limitations:
  • Variability in rehabilitation frequency and intensity was not standardized across participants.
  • The study did not investigate the reasons for interindividual and intertransfer variability in treatment response.
Conclusion:

Establishing neurophysiological recovery profiles is important for understanding recovery after nerve transfer surgery.

Sources:

Original Source(s)

Neurophysiological Recovery Following Nerve Transfer Surgery to Restore Upper Limb Function after Cervical Spinal Cord Injury

  • by Kyle J. Missen, Justin M. Brown, Ross M. Mandeville, Harvey Wu, Sean Bristol, Peter K. Broadhurst, Erin Brown, Christopher Doherty, Amy K. Hanlan, Russell O'Connor, Lawrence R. Robinson, Kayton Rotenberg, J. Michael Hendry, Jana Dengler, Michael J. Berger

  • July 6, 2026

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