Does Solution Choice Impact Midday Fogging? - Summary - MDSpire

Does Solution Choice Impact Midday Fogging?

  • By

  • Melissa Barnett, OD, FAAO, FSLS

  • November 1, 2025

  • 4 min

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Objective:

To evaluate the effect of high-viscosity sodium hyaluronate solution on midday fogging in scleral lens wearers.

Key Findings:
  • Low-contrast visual acuity remained stable in eyes with sodium hyaluronate but decreased in those with saline.
  • Optical density and turbidity increased over time regardless of the filling solution.
  • No significant differences in lens settling rates or magnitudes between the two groups.
Interpretation:

High-viscosity sodium hyaluronate may enhance low-contrast visual performance in keratoconus patients without negatively affecting fluid turbidity or lens settling.

Limitations:
  • Study limited to a small sample size of 22 individuals.
  • Results may not be generalizable to all scleral lens wearers.
Conclusion:

Using high-viscosity sodium hyaluronate can improve visual performance in scleral lens wearers with keratoconus, potentially offering a solution to midday fogging.

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