A Longitudinal Description of the Health-Related Quality of Life Among Individuals at High Risk After SARS-CoV-2 Infection: A Dutch Multicenter Observational Cohort Study - Summary - MDSpire

A Longitudinal Description of the Health-Related Quality of Life Among Individuals at High Risk After SARS-CoV-2 Infection: A Dutch Multicenter Observational Cohort Study

  • By

  • Magda Vergouwe

  • Emma Birnie

  • Sarah van Veelen

  • Jason J Biemond

  • Brent Appelman

  • Hessel Peters-Sengers

  • Godelieve J de Bree

  • Stephanie Popping

  • W Joost Wiersinga

  • on behalf of the

  • TURN-COVID Study Group

  • Matthijs R A Welkers

  • Frans J van Ittersum

  • Maarten F Schim van der Loeff

  • Marije K Bomers

  • Marie José Kersten

  • Mette D Hazenberg

  • Jarom Heijmans

  • Marc van der Valk

  • E Marleen Kemper

  • Marcel van den Berge

  • Heidi S M Ammerlaan

  • Marvin A H Berrevoets

  • Robbert J van Alphen

  • Renée A Douma

  • Eliane M S Leyten

  • Cees van Nieuwkoop

  • Rob J van Marum

  • Frits R Rosendaal

  • Mark G J de Boer

  • Astrid M L Oude Lashof

  • Marit G A van Vonderen

  • Jiri F P Wagenaar

  • Janneke E Stalenhoef

  • Frank van de Veerdonk

  • Robert-Jan Hassing

  • Robin Soetekouw

  • Hazra S Moeniralam

  • Frits van Osch

  • January 30, 2025

  • 0 min

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Objective:

To assess the longitudinal impact of COVID-19 on health-related quality of life (HRQoL) and employment status in high-risk individuals over 12 months.

Key Findings:
  • Median HRQoL utility score declined from 0.85 pre-COVID-19 to 0.81 at 12 months post-COVID-19 (P = .007).
  • Solid organ transplant recipients and patients requiring oxygen therapy were at higher risk for HRQoL decline (P < .05).
  • 45.3% of employed participants reported sick leave related to COVID-19 symptoms, correlating with lower HRQoL scores (P < .01).
Interpretation:

The study highlights a significant decline in HRQoL among high-risk individuals post-COVID-19, emphasizing the ongoing burden of the disease and the need for preventive measures and healthcare policy adjustments.

Limitations:
  • The study may not fully represent all high-risk populations due to specific inclusion criteria.
  • Potential recall bias in pre-COVID-19 HRQoL assessments.
  • The time frame of the study may influence the generalizability of the findings.
Conclusion:

High-risk individuals experience substantial HRQoL decline post-COVID-19, with a notable impact on employment, underscoring the need for continued support, preventive strategies, and further research.

Original Source(s)

A Longitudinal Description of the Health-Related Quality of Life Among Individuals at High Risk After SARS-CoV-2 Infection: A Dutch Multicenter Observational Cohort Study

  • by Magda Vergouwe, Emma Birnie, Sarah van Veelen, Jason J Biemond, Brent Appelman, Hessel Peters-Sengers, Godelieve J de Bree, Stephanie Popping, W Joost Wiersinga, on behalf of the, TURN-COVID Study Group, Matthijs R A Welkers, Frans J van Ittersum, Maarten F Schim van der Loeff, Marije K Bomers, Marie José Kersten, Mette D Hazenberg, Jarom Heijmans, Marc van der Valk, E Marleen Kemper, Marcel van den Berge, Heidi S M Ammerlaan, Marvin A H Berrevoets, Robbert J van Alphen, Renée A Douma, Eliane M S Leyten, Cees van Nieuwkoop, Rob J van Marum, Frits R Rosendaal, Mark G J de Boer, Astrid M L Oude Lashof, Marit G A van Vonderen, Jiri F P Wagenaar, Janneke E Stalenhoef, Frank van de Veerdonk, Robert-Jan Hassing, Robin Soetekouw, Hazra S Moeniralam, Frits van Osch

  • January 30, 2025

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