Modifiable Psychological Factors are Associated With Clusters of Pain, Fatigue, Fecal Incontinence, and Irritable Bowel Syndrome-Type Symptoms in Inflammatory Bowel Disease: A Latent Profile Analysis - Summary - MDSpire
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Modifiable Psychological Factors are Associated With Clusters of Pain, Fatigue, Fecal Incontinence, and Irritable Bowel Syndrome-Type Symptoms in Inflammatory Bowel Disease: A Latent Profile Analysis
To identify symptom profile subgroups in IBD patients and their psychological correlates, enabling tailored treatment pathways.
Key Findings:
Three symptom profiles identified: Moderate (50%), High (40%), and Severe (10%).
Female gender, comorbidity, time since diagnosis, and IBS-type symptoms linked to High and Severe profiles.
Depression, anxiety, negative symptom perceptions, and avoidance behaviors increased risk for High and Severe profiles.
Symptoms persisted in many participants even in clinical remission.
Interpretation:
Cognitive behavioral factors significantly impact symptom severity in IBD, suggesting a need for integrated treatment approaches that combine medical and psychological interventions for improved patient outcomes.
Limitations:
Study focused on self-reported measures, which may introduce bias due to subjective interpretation.
Findings may not be generalizable to all IBD populations.
Conclusion:
Recognizing cognitive behavioral influences on IBD symptoms can lead to earlier identification of patients needing support and more personalized treatment plans, ultimately enhancing patient care.
by Vari Wileman, Joseph Chilcot, Christine Norton, Ailsa Hart, Laura Miller, Imogen Stagg, Natasha Seaton, Richard Pollok, Qasim Aziz, Rona Moss-Morris
