Objective:

To characterize the safety and efficacy of oral and topical prebiotics, probiotics, and postbiotics in managing acne vulgaris.

Approach:

Key Findings:

• 33 studies involving 2112 patients were included, indicating a significant body of evidence.
• Prebiotics, probiotics, and postbiotics may modulate the gut-skin axis and microbiome, potentially enhancing traditional acne therapies.
• These agents could serve as complementary treatments alongside traditional acne therapies.

Interpretation:

The findings suggest that microbiome-modulatory agents may provide additional benefits in managing acne vulgaris, highlighting the importance of the gut-skin axis.

Limitations:

• The review included only studies published until August 2023.
• Exclusion of case reports and nonhuman studies may limit the breadth of evidence.

Conclusion:

Prebiotics, probiotics, and postbiotics show promise in managing acne vulgaris, warranting further research to establish their efficacy and safety, particularly in clinical settings.

Source

Based on findings from:

The Role of Prebiotics, Probiotics, and Postbiotics in Managing Acne Vulgaris: A Comprehensive Review

Peyton V. Warp, Sophie M. Bilik, Lina M. Ferrari, Jonette E. Keri. Dermatology And Therapy, 2026.

https://link.springer.com/article/10.1007/s13555-026-01659-4

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.