Mapping the gut microbiota-diabetic peripheral neuropathy research landscape: a bibliometric analysis of emerging trends and translational frontiers - Summary - MDSpire
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Mapping the gut microbiota-diabetic peripheral neuropathy research landscape: a bibliometric analysis of emerging trends and translational frontiers
To conduct a bibliometric analysis of publications on gut microbiota and diabetic peripheral neuropathy (DPN) from 2010 to 2023, delineating growth trajectories, thematic evolution, research hotspots, and foundational studies.
Key Findings:
133 publications were included, showing exponential growth post-2018 with an average annual increase of 35.7%.
Core research clusters identified include gut microbiota, neuropathic pain, gut-brain axis, and therapeutic interventions such as fecal microbiota transplantation (FMT).
Keyword analysis indicated a shift from foundational concepts like oxidative stress and inflammation to interventional strategies and causal inference approaches.
Interpretation:
The research field is evolving from establishing associative links between gut microbiota and DPN to elucidating causal mechanisms. This shift emphasizes the need for evaluating targeted interventions.
Limitations:
The analysis is limited to publications in English, which may exclude relevant studies in other languages.
Only original research and review articles were included, potentially excluding relevant studies.
Conclusion:
This bibliometric analysis highlights the transition towards a multi-mechanistic gut-brain axis model and emphasizes future research priorities in clinical translation and personalized therapies.
