To report the first case of an intracranial ganglion cell tumor in a patient with ROHHAD syndrome and discuss its classification based on the findings.
Key Findings:
The patient exhibited rapid weight gain and hypoventilation, consistent with ROHHAD syndrome.
An intracranial ganglion cell tumor was found, which is rare in ROHHAD syndrome cases.
Pathological analysis confirmed the tumor as a low-grade ganglion cell tumor.
Interpretation:
The presence of an intracranial tumor in this patient raises questions about the classification of tumors associated with ROHHAD syndrome, as discussed in the source.
Limitations:
The case is a single report and may not represent broader trends as noted in the source.
Further studies are needed to understand the implications of intracranial tumors in ROHHAD syndrome, as suggested in the source.
Conclusion:
This case highlights the need for awareness of both extra- and intracranial neural crest tumors in patients with rapid-onset obesity, as indicated in the source.
by Nathalie J. Doelman-Oldenburger, Antoinette Y. N. Schouten-van Meeteren, Mariette E. G. Kranendonk, Kim Boshuisen, Michiel A. G. E. Bannier, Hanneke M. van Santen
