Integrated left ventricular geometry–function phenotypes and long-term outcomes after acute myocardial infarction - Summary - MDSpire

Integrated left ventricular geometry–function phenotypes and long-term outcomes after acute myocardial infarction

  • By

  • Seonmin Park

  • Seok Oh

  • Yongwhan Lim

  • Joon Ho Ahn

  • Dae Young Hyun

  • Seung Hun Lee

  • Kyung Hoon Cho

  • Min Chul Kim

  • Doo Sun Sim

  • Ju Han Kim

  • Youngkeun Ahn

  • Myung Ho Jeong

  • Jong Pil Park

  • Jay Young Rhew

  • Young Joon Hong

  • June 22, 2026

  • 0 min

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Objective:

To investigate the combined prognostic impact of left ventricular (LV) dilatation and systolic dysfunction in patients with acute myocardial infarction (AMI).

Approach:
    Key Findings:
    • The incidence of MACCE increased stepwise from group A to D (13.2%, 13.5%, 16.8%, and 21.9%, respectively).
    • In fully adjusted analyses, LV dilatation was not associated with increased risk in patients with preserved LVEF (group B vs. group A: HR, 1.13; 95% CI, 0.99–1.29).
    • In contrast, LV dilatation was associated with a higher risk when accompanied by reduced LVEF (group C: HR, 1.12 (1.01–1.24); group D: HR, 1.44 (1.29–1.60)).
    Interpretation:

    Limitations:
    • The study is observational and may be subject to confounding factors.
    • Data derived from a single country may limit generalizability.
    Conclusion:

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