Prevalence and characteristics of persistent pain among head and neck cancer survivors: a systematic review and meta-analysis - Summary - MDSpire

Prevalence and characteristics of persistent pain among head and neck cancer survivors: a systematic review and meta-analysis

  • By

  • Miguel Ángel Fernández-Gualda

  • Paula Postigo-Martin

  • Maria Fernandez-Gonzalez

  • Lydia Martin-Martin

  • Pilar Vargas-Arrabal

  • Mario Lozano-Lozano

  • Carolina Fernández-Lao

  • April 28, 2025

  • 0 min

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Objective:

To identify the prevalence and characteristics of persistent pain among head and neck cancer survivors, emphasizing the importance of understanding these factors for improved patient care.

Key Findings:
  • The prevalence of persistent pain among head and neck cancer survivors is 31% (95% CI, 20 to 42), indicating a significant health concern.
  • Meta-regression explained approximately 40% of the observed heterogeneity (R2 = 40.57), suggesting variability in study results.
  • A significant portion of head and neck cancer survivors experience persistent pain post-treatment, highlighting the need for targeted interventions.
Interpretation:

The findings indicate that nearly one-third of head and neck cancer survivors suffer from persistent pain, underscoring the urgent need for better pain management strategies in clinical practice.

Limitations:
  • Considerable variability in methods used across studies, including differences in pain assessment tools and treatment protocols.
  • Inability to draw definitive conclusions regarding the impact of cancer location, treatment, and pain assessment methods on prevalence due to study heterogeneity.
Conclusion:

The study underscores the prevalence of persistent pain in head and neck cancer survivors and the necessity for tailored therapeutic approaches, while also calling for further research to explore these issues.

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