Objective:

To present a case of neurological improvement in an adolescent with advanced neuro-Wilson disease following liver transplantation.

Approach:

Key Findings:

• The patient's UWDRS score improved from 162 at presentation to 59 at one year post-transplant.
• Marked recovery included return of speech, normalization of cognitive engagement, decreased contractures, and ability to walk with support.

Interpretation:

Significant neurological improvement is possible in adolescents with advanced neuro-Wilson disease following timely liver transplantation, suggesting that restoration of copper metabolism and structured rehabilitation can lead to substantial functional recovery.

Limitations:

• The findings are based on a single case report, limiting generalizability.
• Long-term outcomes require further investigation.

Conclusion:

This case illustrates the potential for neurological improvement in patients with Wilson disease post-liver transplantation.

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.