To investigate factors that predispose patients with hypertensive intracerebral hemorrhage to develop hypotension after intubation.
Approach:
Study Design: Single-center, retrospective observational study involving 451 patients with hypertensive intracerebral hemorrhage.
Patient Selection: 275 patients met eligibility criteria and were divided into hypotensive (124 cases) and non-hypotensive (151 cases) groups based on blood pressure changes after intubation.
Data Analysis: Comparison of demographic data, vital signs, and laboratory results between groups, followed by logistic regression to identify predictors of hypotension.
Key Findings:
Significant differences in age, weight, pre-existing cardiovascular conditions, BMI, albumin, and BNP were observed between hypotensive and non-hypotensive groups.
Underweight individuals and those with elevated BNP were found to be more likely to experience post-intubation hypotension.
Interpretation:
Older age, low body weight, multiple comorbidities, hypoalbuminemia, and elevated BNP were associated with post-intubation hypotension, with low body weight and elevated BNP identified as independent predictors.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce selection bias.
Conclusion:
Emergency physicians should identify high-risk patients for post-intubation hypotension and consider pre-emptive measures.