Objective:

To determine whether IL-18 -137G/C (rs187238) and IL-21-1472G/T (rs2055979) SNPs impact the risk and progression of MS in Egyptian patients and their influence on clinical outcomes.

Approach:

Key Findings:

• The research aims to provide insights into the genetic factors influencing MS risk and progression.

Interpretation:

Limitations:

• The study is limited to a specific population in Egypt, which affects the generalizability of the results.
• Exclusion criteria limit the diversity of the patient cohort.

Conclusion:

Source

Based on findings from:

Impact of genetic polymorphisms in the interleukin-18 and interleukin-21 genes on the risk and clinical outcomes of multiple sclerosis

Noha M. Bakr, Noha A. Hashim, Mohamed Adel El-Eshmawy, Hatim A. El-Baz. Bmc Neurology, 2026.

https://link.springer.com/article/10.1186/s12883-026-04869-7

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