Premenstrual syndrome, premenstrual dysphoric disorder, and coping strategies in women with menstrual migraine - Summary - MDSpire

Premenstrual syndrome, premenstrual dysphoric disorder, and coping strategies in women with menstrual migraine

  • By

  • Alshimaa S. Othman

  • Mona Hussein

  • Alaa Elmazny

  • Salsabil Abo Al-Azayem

  • Azza Elashiry

  • Mennat-Allah Tarek

  • Heba Qassim Shamardal

  • Sara El-Sayed Abd El-Ghani

  • Mohamed Wagdy

  • Eman Hany Elsebaie

  • Doaa Lotfy Abd El Baky

  • Rehab Magdy

  • May 29, 2026

  • 0 min

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Objective:

To investigate the severity of PMS, PMDD, and coping strategies among women with menstrual migraine (MM) versus those with non-MM, and their impact on perceived headache burden.

Key Findings:
  • Females with MM had significantly higher PSST and HIT-6 scores compared to the non-MM group (p = 0.001, 0.002).
  • PMDD was confirmed in 5.6% of females with MM and 1.9% without MM (p = 0.06).
  • PMDD presence was associated with a 3.113 point increase in HIT-6 scores (95%CI: 0.607–5.915, p = 0.016).
  • Higher PSST scores and lower awareness and acceptance scores correlated with higher HIT-6 scores (p ≤ 0.001).
Interpretation:

Women with PMDD and high PMS severity are at risk for increased headache burden. Lower use of awareness and acceptance coping strategies further exacerbates this risk.

Limitations:
  • The study's cross-sectional design limits causal inferences.
  • Exclusion of women on hormonal treatments or migraine preventive medications may affect generalizability, potentially underrepresenting the broader population.
Conclusion:

Women with PMDD and high PMS severity are at risk for increased headache burden, emphasizing the need for effective coping strategies.

Original Source(s)

Premenstrual syndrome, premenstrual dysphoric disorder, and coping strategies in women with menstrual migraine

  • by Alshimaa S. Othman, Mona Hussein, Alaa Elmazny, Salsabil Abo Al-Azayem, Azza Elashiry, Mennat-Allah Tarek, Heba Qassim Shamardal, Sara El-Sayed Abd El-Ghani, Mohamed Wagdy, Eman Hany Elsebaie, Doaa Lotfy Abd El Baky, Rehab Magdy

  • May 29, 2026

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