Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study - Summary - MDSpire
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Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • By

  • Xinyi Wang

  • Ke Qiu

  • Yuyang Zhang

  • Sen Yang

  • Yanhong Xu

  • Xiaosong Mu

  • Yaxin Luo

  • Wendu Pang

  • Jiangnan Han

  • Chunhong Hu

  • Jia Chen

  • Ning Ma

  • Wen He

  • Wei Dai

  • Yang Zou

  • Lingfeng Xiong

  • Hongchang Chen

  • Weifeng Chen

  • Dengyun Zhang

  • Guanghui Zhang

  • Zhen Hu

  • Lintong Dai

  • Xiaohai Liu

  • Bingcai He

  • Xiaobing Pu

  • Wei Xu

  • Jianjun Ren

  • Yu Zhao

  • November 28, 2025

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Objective:

To assess the clinical effectiveness of standard care (systemic steroid and systemic steroid combined with batroxobin) with and without personalized acoustic therapy (AT) on ISSHL-related tinnitus, specifically focusing on the comparative outcomes.

Key Findings:
  • ISSHL affects 10-27 cases/100,000 people annually, with 90% of cases accompanied by tinnitus, highlighting the prevalence of this condition.
  • Current treatments show limited efficacy in alleviating acute tinnitus, indicating a need for alternative approaches.
  • Personalized AT may provide a novel approach for managing ISSHL-related tinnitus, potentially addressing the shortcomings of existing treatments.
Interpretation:

The study aims to evaluate whether combining standard care with personalized AT can improve outcomes for patients suffering from tinnitus due to ISSHL, with a focus on enhancing treatment efficacy.

Limitations:
  • Limited existing evidence on the efficacy of acoustic therapy for tinnitus, which may affect the generalizability of findings.
  • Potential biases in participant selection and treatment allocation that could influence the study's outcomes.
Conclusion:

The trial seeks to establish more effective management strategies for ISSHL-related tinnitus, addressing a significant gap in current treatment protocols and potentially improving patient quality of life.

Sources:

Original Source(s)

Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • by Xinyi Wang, Ke Qiu, Yuyang Zhang, Sen Yang, Yanhong Xu, Xiaosong Mu, Yaxin Luo, Wendu Pang, Jiangnan Han, Chunhong Hu, Jia Chen, Ning Ma, Wen He, Wei Dai, Yang Zou, Lingfeng Xiong, Hongchang Chen, Weifeng Chen, Dengyun Zhang, Guanghui Zhang, Zhen Hu, Lintong Dai, Xiaohai Liu, Bingcai He, Xiaobing Pu, Wei Xu, Jianjun Ren, Yu Zhao

  • November 28, 2025

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