Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study - Summary - MDSpire

Comparative Effectiveness of Conventional Treatment and Acoustic Therapy for Acute Tinnitus in Patients with Idiopathic Sudden Sensorineural Hearing Loss: A Randomized Controlled Study

  • By

  • Xinyi Wang

  • Ke Qiu

  • Yuyang Zhang

  • Sen Yang

  • Yanhong Xu

  • Xiaosong Mu

  • Yaxin Luo

  • Wendu Pang

  • Jiangnan Han

  • Chunhong Hu

  • Jia Chen

  • Ning Ma

  • Wen He

  • Wei Dai

  • Yang Zou

  • Lingfeng Xiong

  • Hongchang Chen

  • Weifeng Chen

  • Dengyun Zhang

  • Guanghui Zhang

  • Zhen Hu

  • Lintong Dai

  • Xiaohai Liu

  • Bingcai He

  • Xiaobing Pu

  • Wei Xu

  • Jianjun Ren

  • Yu Zhao

  • November 28, 2025

  • 0 min

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Objective:

To assess the clinical effectiveness of standard care (systemic steroid and systemic steroid combined with batroxobin) with and without personalized acoustic therapy (AT) on ISSHL-related tinnitus, specifically focusing on the comparative outcomes.

Key Findings:
  • ISSHL affects 10-27 cases/100,000 people annually, with 90% of cases accompanied by tinnitus, highlighting the prevalence of this condition.
  • Current treatments show limited efficacy in alleviating acute tinnitus, indicating a need for alternative approaches.
  • Personalized AT may provide a novel approach for managing ISSHL-related tinnitus, potentially addressing the shortcomings of existing treatments.
Interpretation:

The study aims to evaluate whether combining standard care with personalized AT can improve outcomes for patients suffering from tinnitus due to ISSHL, with a focus on enhancing treatment efficacy.

Limitations:
  • Limited existing evidence on the efficacy of acoustic therapy for tinnitus, which may affect the generalizability of findings.
  • Potential biases in participant selection and treatment allocation that could influence the study's outcomes.
Conclusion:

The trial seeks to establish more effective management strategies for ISSHL-related tinnitus, addressing a significant gap in current treatment protocols and potentially improving patient quality of life.

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