Utilizing Active Fluidics at Reduced Intraocular Pressure Alleviates Intraoperative Discomfort During Phacoemulsification: A Propensity Score-Matched Analysis - Summary - MDSpire

Utilizing Active Fluidics at Reduced Intraocular Pressure Alleviates Intraoperative Discomfort During Phacoemulsification: A Propensity Score-Matched Analysis

  • By

  • Yuanjiao Qiao

  • Ye Ye

  • Fangyan Liu

  • Lishi Luo

  • Xiaosheng Huang

  • Biyun Liang

  • Wenqun Xi

  • Xinhua Liu

  • Kun Zeng

  • April 22, 2026

  • 0 min

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Objective:

To compare intraoperative discomfort and early postoperative outcomes between phacoemulsification using the Centurion Vision System (active fluidics at lower intraocular pressure) and the Stellaris Elite System (gravity-based fluidics at higher IOP).

Key Findings:
  • Active Fluidics Group had significantly fewer patients requiring supplemental anesthesia (3.1% vs. 13.8%; p = 0.028).
  • Median pain scores were lower in the Active Fluidics Group (1 vs. 3; p < 0.001).
  • Day-1 CCT increase was smaller with active fluidics (28.4 vs. 46.8 μm; p < 0.001).
  • No intraoperative complications occurred, and ECD loss and final visual acuity were comparable between groups.
Interpretation:

Phacoemulsification using active fluidics at lower IOP significantly reduces intraoperative discomfort and early postoperative corneal edema, while ensuring safety and maintaining visual outcomes.

Limitations:
  • Single-center study may limit generalizability; results may not apply to broader populations.
  • Short follow-up period of 1 month may not capture long-term outcomes, necessitating further research.
Conclusion:

Active fluidics technology improves patient comfort during phacoemulsification and reduces early postoperative corneal edema without compromising safety or visual outcomes.

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