Incidence of herpes zoster among individuals vaccinated against COVID-19 and/or those who have contracted the virus: a cross-sectional analysis - Summary - MDSpire

Incidence of herpes zoster among individuals vaccinated against COVID-19 and/or those who have contracted the virus: a cross-sectional analysis

  • By

  • Nebiha Gozde Ispir

  • Umut Pamukcu

  • Ahmet Hursit Ispir

  • Ilkay Peker

  • Meryem Toraman

  • February 7, 2026

  • 0 min

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Objective:

To investigate the incidence of herpes zoster (HZ) in individuals who have received the COVID-19 vaccine and/or had COVID-19, emphasizing the significance of understanding its relationship with COVID-19 or the vaccine in ongoing research.

Key Findings:
  • Increased incidence of herpes zoster was observed in individuals post-COVID-19 vaccination, suggesting a need for monitoring.
  • The relationship between COVID-19 infection and herpes zoster incidence was also noted, indicating potential implications for patient care.
  • Self-reported data indicated a potential link between vaccine administration and HZ reactivation, warranting further investigation.
Interpretation:

The findings suggest a possible association between COVID-19 vaccination and the reactivation of herpes zoster, warranting further investigation into the underlying mechanisms and their clinical significance.

Limitations:
  • Self-reported data may introduce bias.
  • The study's cross-sectional design limits causal inferences.
  • Sample size may not fully represent the broader population.
  • Potential confounding factors were not controlled for.
Conclusion:

The study highlights the need for ongoing monitoring of herpes zoster incidence in vaccinated populations and further research to understand the implications of these findings, particularly in relation to patient management strategies.

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