Beyond the Auditory: Anxiety Bridges Sleep Disturbances and Depressive Symptoms to Tinnitus Handicap - Summary - MDSpire

Beyond the Auditory: Anxiety Bridges Sleep Disturbances and Depressive Symptoms to Tinnitus Handicap

  • By

  • Fan, Lijuan

  • Fan, LiTing

  • Wu, Qiqi

  • Zhou, Jie

  • Wu, Liya

  • Hu, Hantong

  • Gao, Hong

  • May 11, 2026

  • 0 min

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Objective:

To explore how anxiety, sleep disturbances, and depression interact to influence tinnitus severity.

Key Findings:
  • Tinnitus severity positively correlated with SRSS, SDS, and SAS scores (all P < 0.05).
  • Age, sleep quality, and anxiety identified as independent predictors of increased THI scores.
  • Anxiety partially mediated the relationship between sleep disturbances and THI (mediation effect: 31.7%) and fully mediated the relationship between depression and THI.
  • Mediating effect of anxiety was more pronounced in middle-aged and elderly individuals, females, and patients with left-sided tinnitus.
Interpretation:

Anxiety is a central mediating mechanism linking sleep disturbances and depressive symptoms to tinnitus severity.

Limitations:
Conclusion:

The findings highlight the critical role of anxiety in the relationship between psychological factors and tinnitus distress.

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