OCT Shows Slowing of Structural Glaucoma Progression After SLT  - Summary - MDSpire

OCT Shows Slowing of Structural Glaucoma Progression After SLT 

  • By

  • Julie Greenbaum, editor

  • Julie Greenbaum, editor

  • May 1, 2026

  • 3 min

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Objective:

To evaluate the impact of selective laser trabeculoplasty (SLT) on structural glaucomatous progression as measured by optical coherence tomography (OCT).

Key Findings:
  • Prior to SLT, significant progressive thinning of RNFL thickness was observed.
  • After SLT, rates of change for all evaluated OCT parameters were no longer significantly different from zero.
  • Significant slowing of average RNFL thickness, superior RNFL, and cup-to-disc ratio progression was noted post-SLT.
  • A modest but statistically significant reduction in mean IOP was observed following SLT.
Interpretation:

SLT may not only lower IOP but also slow the structural progression of glaucomatous damage over time, as evidenced by OCT measurements.

Limitations:
  • Small sample size of 25 eyes.
  • Retrospective nature of the study may limit causal inferences.
Conclusion:

SLT is a meaningful therapeutic option that may help preserve the optic nerve and should be considered for earlier use in glaucoma management.

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