Precision approach for transradial access during PCI: a state-of-the-art review - Summary - MDSpire

Innovative Strategies for Transradial Access in Percutaneous Coronary Intervention: A Comprehensive Review

  • By

  • Tanawat Attachaipanich

  • Muzamil Khawaja

  • Hafeez Ul Hassan Virk

  • Dmitriy N. Feldman

  • Elmir Omerovic

  • Ian C. Gilchrist

  • Arnold H. Seto

  • Chayakrit Krittanawong

  • July 21, 2026

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Objective:

To summarize contemporary evidence on transradial approach (TRA) for coronary angiography and percutaneous coronary intervention (PCI), focusing on technical considerations, adjunctive pharmacology, access-site complications, and future perspectives.

Approach:
  • Technical Refinements: Discusses variations in puncture technique, use of vasodilator cocktails, and strategies to reduce radial artery occlusion.
  • Comparative Analysis: Compares TRA with transfemoral access (TFA) in terms of bleeding, vascular complications, and mortality in acute coronary syndromes.
  • Future Research Directions: Identifies the need for further research on anticoagulation strategies and alternative access methods like distal radial and ulnar approaches.
Key Findings:
  • TRA reduces bleeding and vascular complications compared to TFA.
  • TRA is associated with lower mortality in patients with acute coronary syndromes.
  • Technical refinements and adjunctive pharmacology can enhance procedural success with TRA.
  • Alternative access strategies like distal radial and ulnar approaches have advantages but are limited by higher crossover rates.
Interpretation:

Limitations:
  • Optimal anticoagulation strategies in the TRA era remain uncertain.
  • Higher crossover rates and longer cannulation times for alternative access strategies may limit their use.
Conclusion:

Sources:

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