Analysis of Risk Factors and Construction of a Prediction Model for Preoperative Concurrent Pathogenic Pyuria in Patients With Ureteral Calculi - Summary - MDSpire

Analysis of Risk Factors and Construction of a Prediction Model for Preoperative Concurrent Pathogenic Pyuria in Patients With Ureteral Calculi

  • By

  • Hengjiang Wu

  • Wei Zheng

  • Huayu Bao

  • Yuandi Fu

  • Chunhua Lin

  • Zhiguang Liao

  • Yijun Ye

  • Mengzhao Wei

  • Yu Zhang

  • December 11, 2025

  • 0 min

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Objective:

To analyze risk factors for preoperative pyuria in patients with ureteral calculi and develop a predictive model for concurrent pathogenic pyuria.

Key Findings:
  • 630 patients (53.30%) were diagnosed with pyuria.
  • Independent risk factors for preoperative pyuria: female gender, bilateral UC, stone size, hydronephrosis size.
  • For pathogenic pyuria: female gender, comorbid diabetes mellitus, hydronephrosis size > 40 mm.
  • Prediction model showed an area under the ROC curve of 0.764, indicating good predictive ability.
Interpretation:

The study confirms significant risk factors for preoperative pyuria and pathogenic pyuria, providing a model for early intervention.

Limitations:
  • Retrospective design may introduce bias.
  • Single-center study limits generalizability.
Conclusion:

The developed prediction model can effectively assess the risk of preoperative concurrent pathogenic pyuria, aiding in early clinical interventions.

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