Effects of Immersive Virtual Reality Interventions on Symptom Management in Patients With Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials - Summary - MDSpire

Effects of Immersive Virtual Reality Interventions on Symptom Management in Patients With Gastrointestinal Cancer: Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • By

  • Fangping Chen

  • Xingyue Guo

  • Ran Wang

  • Yan Li

  • Didi Xu

  • Yongzhen Wang

  • Wei Kong

  • Yin Chen

  • Luyang Jin

  • Xuemei Xian

  • July 2, 2026

  • 0 min

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Objective:

To comprehensively evaluate the effectiveness of immersive virtual reality (IVR) interventions for symptom management in patients with gastrointestinal cancer, focusing on anxiety, pain, and other relevant indicators.

Approach:
  • Design: The meta-analysis was conducted according to the PRISMA 2020 statement and registered in the PROSPERO database.
  • Search Strategy: A systematic search was conducted across 12 databases and 1 gray literature source, covering various medical and scientific databases.
Key Findings:
  • Gastrointestinal cancers account for a significant portion of cancer-related morbidity and mortality.
  • Patients with gastrointestinal cancer often experience both physical pain and psychological distress.
  • Existing interventions typically target either physical or psychological symptoms, with limited integrated approaches.
  • Preliminary studies suggest IVR may reduce anxiety and pain, improve quality of life, and shorten hospital stays.
Interpretation:

The findings aim to provide evidence-based guidance for implementing IVR in clinical practice and inform future research designs.

Limitations:
  • Existing systematic reviews include heterogeneous cancer populations without stratification by tumor type.
  • There is substantial variability in intervention protocols across studies.
  • Lack of in-depth analysis of moderating factors such as intervention timing and session duration.
Conclusion:

The systematic review and meta-analysis seeks to fill the gap in high-quality evaluations of IVR for gastrointestinal cancer symptom management.

Sources:

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