Latent Healthcare Stigma Profiles and Their Association With Human Immunodeficiency Virus (HIV) Treatment and Care Outcomes Among Women With HIV in the United States: An Intersectional Analysis - Summary - MDSpire

Latent Healthcare Stigma Profiles and Their Association With Human Immunodeficiency Virus (HIV) Treatment and Care Outcomes Among Women With HIV in the United States: An Intersectional Analysis

  • By

  • Jennifer P Jain

  • Nadra E Lisha

  • Jae Sevelius

  • Torsten B Neilands

  • Carol Dawson-Rose

  • Mallory O Johnson

  • Ayden Scheim

  • Bulent Turan

  • Adebola Adedimeji

  • Mirjam-Colette Kempf

  • Gypsyamber D’Souza

  • Michelle Floris-Moore

  • Seble Kassaye

  • Anandi Sheth

  • Azure Thompson

  • Deborah Jones Weiss

  • Phyllis C Tien

  • August 6, 2025

  • 0 min

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Objective:

To estimate associations between latent stigma profiles and HIV outcomes among women living with HIV (WWH) in the United States, emphasizing the role of intersectionality.

Key Findings:
  • Identified three stigma profiles: high stigma (3%), low stigma (86%), and anticipated stigma (11%).
  • High stigma profile membership was significantly associated with being Black, drug use, suboptimal adherence, depression, and PTSD, indicating critical areas for intervention.
  • Suboptimal adherence was lowest in the low stigma profile and predicted future viral nonsuppression.
Interpretation:

Reducing stigma and integrating HIV, substance use, and mental health treatment is crucial for improving health outcomes among WWH in the US, particularly for those in high stigma profiles.

Limitations:
  • The study may not generalize to all women with HIV due to the specific cohort, which may limit the applicability of findings.
  • Potential biases in self-reported data on stigma and substance use could affect the reliability of the results.
Conclusion:

Addressing intersectional stigma is essential for enhancing HIV treatment outcomes among women, particularly those who are Black and use drugs, and should inform targeted interventions.

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